Pathway analysis

Network‐Based Approaches for Pathway Level Analysis

Identification of impacted pathways is an important problem because it allows us to gain insights into the underlying biology beyond the detection of differentially expressed genes. In the past decade, a plethora of methods have been developed for …

MicroRNA-augmented pathways (mirAP) and their applications to pathway analysis and disease subtyping

MicroRNAs play important roles in the development of many complex diseases. Because of their importance, the analysis of signaling pathways including miRNA interactions holds the potential for unveiling the mechanisms underlying such diseases. …